Stanford's AI-discovered peptide BRP cuts food intake by up to 50% in animals

emmanuelvivier · x · 2026-11-07

Stanford Medicine researchers, aided by AI screening, identified a naturally occurring peptide called BRP that reduced food intake by up to 50% in animals and promoted fat loss, mimicking semaglutide (Ozempic) effects. Unlike existing GLP-1 drugs, BRP acts selectively on the brain region controlling hunger and metabolism rather than multiple organs, potentially avoiding nausea, constipation, and significant muscle loss. Human trials are still needed, but it represents another strong case of AI accelerating drug discovery.

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