Bolero traces bulk-tissue eQTLs to cell types, predicts autism non-coding mutation effects
anshulkundaje · x · 2026-10-23
Stanford researcher Anshul Kundaje shared progress on Bolero, a model that traces bulk-tissue eQTLs to the cell types likely driving them. Applied to human genetics, it predicts larger effects for non-coding de novo mutations in autism cases than in siblings, especially in early neuronal development.
Related event: Arc Institute Releases Bolero: Predicting Gene Regulation from DNA Sequence(3 posts)→
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