Bonn scientists reverse 60 years of aging, turning an 80-year-old's blood cells into young neural stem cells

kimmonismus · x · 2026-10-23

Researchers at the University of Bonn directly reprogrammed blood precursor cells from an 80-year-old into neural stem cells, skipping the usual pluripotent stem cell stage. Epigenetic clocks estimate the resulting cells' molecular age at under 20 — a reversal of more than 60 years of cellular aging.

The rejuvenation unfolded gradually and was trackable for over 100 days, offering a new way to study how cells become younger and potentially shedding light on age-related diseases like Alzheimer's.

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