Claude Opus simulated Hox gene networks to generate lizard and snake skeletons

repligate · x · 2026-10-18

X user @4confusedemoji shared results of using Opus 5.5 to simulate Hox gene regulatory networks, producing developmental sketches resembling lizard and snake skeletons.

The figures include annotated vertebral counts — a lizard-like body with 51 vertebrae (15 thoracic, 6 lumbar, 3 sacral) and a snake mutant sibling with 100 vertebrae where thoracic Hox expands and limbs are lost — a playful demo of AI applied to evolutionary developmental biology.

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