Cell fate predictions need not reconstruct every gene, given noisy single-cell data

anshulkundaje · x · 2026-10-10

Anshul Kundaje agrees with Fabian Theis that cell fate prediction is a much better-defined objective than raw perturbation effect prediction: given how poor single-cell measurements are, one could in principle get correct answers without perfectly predicting every gene's expression. This post substantially duplicates other fragments of the same thread.

Related event: Theis and Kundaje Debate Phenotype-First Perturbation Modeling(4 posts)→

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