p53 reactivator Rezatapopt synergizes with PI3Kα inhibitors to slow cancer growth in mice

adam_thiesen · x · 2026-11-09

Rezatapopt, a p53 reactivator, works synergistically with PI3Kα inhibitors to slow cancer growth both in vitro and in mouse models, suggesting a promising combination therapy strategy for p53-mutant tumors.

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