Prion researcher exposes how mouse survival curves fake significance with broken axes
zakkohane · x · 2026-11-04
A prion researcher with 15 years of experience published a blog post exposing how mouse therapeutic studies present survival curves with broken axes and 6% median survival differences, yet claim positive results from P<0.05. He released data on 301 untreated control animals from 9 years of in vivo studies, modeled how P values can appear significant even for null results, and shared his intuition for judging which claims are believable—claims that have led to high-profile publications, millions in funding, and clinical trials.
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