BATv1 genomics model trained on same data as BPNet, addressing GC-bias confounds

jmschreiber91 · x · 2026-10-31

Responding to concerns that Enformer often confounds TF motifs with open-chromatin GC bias, jmschreiber91 explains that BATv1 is trained on the exact same data and loci as the BPNet models (with slightly different sampling ratios), which handle this issue.

The author is releasing prior to a preprint, inspired by Anshul Kundaje's practice of sharing work publicly early. An AI-for-science (genomics) research update.

Related event: UMass releases BATv1: 46k-parameter model atlas covering 3,429 TF binding experiments(14 posts)→

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