homer2 motif discovery gets 10-100x speedup in unofficial optimized release
jmschreiber91 · x · 2026-10-30
Developers released homer2-ao, a pair of speedups to the homer2 motif discovery and scanning algorithms delivering 10-100x faster runs with a fraction of the memory. Released unofficially because the original authors were unresponsive. The same effort also improved bedtools intersect to 3x speed with one-third the memory.
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