Nature paper releases TenK10K phase 1: single-cell RNA-seq from ~2,000 people maps how genetic variants shape immune gene expression
mo_lotfollahi · x · 2026-10-29
- Anna S. E. Cuomo and colleagues published in Nature the phase 1 release of the TenK10K dataset: matched WGS and single-cell RNA-seq from nearly 2,000 individuals.
- The study systematically maps how rare and common genetic variants shape immune gene expression at single-cell resolution.
- The paper is open access; the project is a large-scale population single-cell genetics effort (ultimately targeting tens of thousands of donors).
Related event: TenK10K project publishes three Nature papers on nine million immune cells(2 posts)→
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