2012 whole-cell model paper shows we can scalably measure only ~5 of the processes needed to simulate biology
niloofar_mire · x · 2026-10-27
Responding to weekend hype about simulating biology, this thread revisits a 2012 whole-cell modeling paper: simulating one cell requires sub-models for dozens of processes — metabolism, transcriptional regulation, DNA replication/repair, RNA processing, translation, protein folding, chromosome segregation and more. Only about 5 of these currently have scalable measurements.
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