Satya Nadella on open vs closed models, trusting chain of thought, and why firms must own their intelligence

20VC · rss · 2026-10-26

20VC published a long interview with Microsoft CEO Satya Nadella, who grew the company from $300BN to $3.9TRN in market cap. Topics include: whether to assume every AI model is compromised, stopping AI agents from causing harm, trusting a model's chain of thought, whether China's open-source lead is a safety risk, open vs closed models over the next two years, why every company should own its own intelligence, whether we're entering an AI implementation economy, whether owning the full stack is required to win, whether the world can support $100B training runs, and whether AI will transform sales, finance and marketing the way it has coding, plus a quickfire round.

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