Tufts team open-sources HAL, showing rat cortical cultures learn to steer network bursts

MacrinePhD · x · 2026-10-25

New bioRxiv research from Michael Levin, Wesley Clawson and teams at Tufts' Allen Discovery Center, Harvard, and Google introduces HAL (Holistic Agential Learning), an open-source closed-loop platform showing that dissociated rat cortical cultures can learn to control where network bursts originate through minimal reinforcement. Key findings: burst initiation zones shift toward the goal side over days while propagation directions are preserved; trained networks recover better from incorrect states rather than just making fewer errors; and performance gains consolidate across days rather than within sessions.

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