RFD4-Proteina doubles enzyme scaffolding pass rate to 12.1% vs 5.7%

AllThingsApx · x · 2026-10-22

On enzyme active-site scaffolding, high-thinking RFD4-Proteina achieved a 12.1% computational clustered pass rate versus 5.7% for AlphaProtein-novo codesign. Charts show thousands of designs per GPU-hour and passing designs on 35/37 tasks. The author invites the community to test it on custom industrial catalysts and share results.

Related event: RFD4-Proteina launches, beating baselines across protein design benchmarks(6 posts)→

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