Clinical trials already hedge against human reward hacking, says Eisen on Tao's AI drug concern

tallinzen · x · 2026-10-12

Responding to Terence Tao's concern about AI reward hacking in drug discovery, Michael Eisen argues it's not new: clinical trials are structurally a hedge against reward hacking by humans and corporations — and are routinely gamed, though by corrupting the process rather than an AI designing something that merely looks effective. He thinks Tao's worry is valid but the example misses the point. tallinzen adds the slide is clearly about alignment/reward hacking, not using drugs without understanding mechanisms.

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