AI Protein Design Still Can't Solve Binder Prediction and the Age-Old Docking Problem, Researcher Explains
anshulkundaje · x · 2026-10-01
In a thread on AI-driven protein design, Alex Campreis highlights two unsolved problems: predicting whether a pre-existing binder actually binds an arbitrary target, and—even when binding is known—predicting which epitope it targets, the classic "docking problem." He asks why AI still fails here.
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