Biological Millennium Problems Should Be Specific, Verifiable Datasets, Argues Poster
owl_posting · x · 2026-09-21
The author proposes that biology's equivalent of the Millennium Prize Problems should be defined as very specific datasets — e.g., a catalog of epitope-resolved nm protein binders across the human proteoform. Solving it would require knowing the full range of human PTMs and isoforms plus scalable generation/testing of epitope-specific binders. Hard but achievable, and crucially verifiable.
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