Open-Source Model Powers Structural Biology Agent Demo
MaziyarPanahi · x · 2026-07-11
This post demonstrates a fully open-source structural biology agent workflow:
- Brain: GLM-5.2
- Vision: Qwen3-VL running via Llama.cpp
- Interface/Rendering: Open-source Mol viewer
- Orchestration: Pydantic AI
- Target: EGFR + erlotinib structure from RCSB PDB
The author mentions that the entire process used just a single prompt to generate 6 render versions. At each step, the vision model provides actual critiques, iterating until the drug's position in the pocket "looks more reasonable." Follow-up replies emphasize that this is a demonstration of open models capable of "doing structural biology on their own."
More from coding & agent
- A GLP1R variant may explain stronger Ozempic weight loss, and the team built an agent workflow — julia_kiseleva · 2026-07-21
- Pinpoint turns a clicked VS Code element into reusable agent context — Scared-Tip7914 · 2026-07-21
- A Claude-coded Chrome extension shames you with a private jet when you open YouTube — alex_verem · 2026-07-21
- A curated TTS list for voice agents tracks latency, cancellation, and evals — mahimairaja · 2026-07-21
- Harness engineering is emerging as the execution layer for reliable AI agents — Pavan_Belagatti · 2026-07-21
- DevFest Lisbon keynote will cover Google AI Studio’s latest vibe coding and agentic AI features — gerardsans · 2026-07-21