Geodesic's NovaAtom-Lite tops AlphaFold 3 on antibody-antigen structure prediction (79.07% vs 47.90%)
QuanquanGu · x · 2026-11-11
Geodesic Intelligence launched NovaAtom-Lite, an all-atom structure prediction model for drug discovery covering proteins, nucleic acids, and bound molecules. On FoldBench antibody-antigen prediction (DockQ ≥ 0.23) it scores 79.07% (n=172), beating Isomorphic Labs' IsoDDE (75.58%) and DeepMind's AlphaFold 3 (47.90%, n=167), evaluated with 5 seeds × 5 samples and top-1 selected by its own ranking score. Live via Geodesic API and NovaDDE.
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