AI agent audits mom's APOE E3/E4 genetic report, with a second AI trying to break the work
kevrussell · x · 2026-11-05
Kevin Russell's mom's genetic report came back APOE E3/E4 (Alzheimer's risk genotype) with a long list of diet, exercise, and supplement suggestions. He had Kram, the Alzheimer's research-map agent at his ProjectForty2 lab, run a full audit: checking the genotype meaning against authoritative sources and verifying every recommendation and citation.
- A second agent, Ford, ran adversarial break-testing; the page only published what survived, with receipts (sources, PMIDs, fixes)
- Kram (MARK spelled backward) is named after the author's parents; the page is explicitly an evidence map, not medical advice, with testing and treatment decisions left to clinicians and genetic counselors
- It also addresses the next generation: an E3/E4 parent leaves open questions for children and grandchildren, and the goal is to pass down evidence rather than noise
A complete case of a multi-agent workflow (generation + adversarial review) applied to auditing personal health information.
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