Cell paper proposes 15 AI grand challenges for cell biology, Hilbert-style
StephenQuake · x · 2026-11-04
A Cell paper led by Andrea Califano with Stephen Quake proposes 15 grand challenges for cell biology—modeled on Hilbert's 23 problems—each paired with a real-world test of AI predictions. Challenges span molecular function, cellular/systems function, and translation, from regulatory network reverse engineering to clinical trial outcome prediction, anchored on a world model trained on perturbational data.
Related event: Cell Paper Proposes 15 Hilbert-Style AI Challenges for Cell Biology(2 posts)→
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