Nature: human-derived organoids wired into mouse cortex, BCI implications

bratton · x · 2026-11-03

Sergiu P. Pașca's Stanford team, with Karl Deisseroth among collaborators, published an open-access Nature paper showing that human-derived brain organoids transplanted into mice form developmental connections with mouse cortex — 'developmental xenocortication' — offering a new window into human brain development, which is otherwise hard to study due to tissue inaccessibility.

Benjamin Bratton, who shared the paper, notes the implications for brain-computer interface research could be significant. The paper (Nature vol. 658) has already drawn 187k accesses.

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