Frontier LLMs still fail basic molecular cloning, researcher says
anshulkundaje · x · 2026-11-01
nlarusstone argues frontier LLMs are still not good at biology — even basic molecular cloning tasks are beyond them. Responding to pushback, he clarifies he believes LLMs will improve on such verifiable-reward tasks, but the result reveals how much tacit knowledge biology holds and how spiky model intelligence is: harder-to-verify tasks like program decisions and target ID will lag further.
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