Molence Bio Open-Sources Mol-1, Matching Closed SOTA at Antibody Structure Prediction
AllThingsApx · x · 2026-10-31
Molence Bio released Mol-1, an open biomolecular model for antibody structure prediction. On FoldBench-AB it hits 88.3% success unconstrained and 75.0% median success at DockQ > 0.23, essentially matching closed-source IsoDDE's reported 75.58% and beating OpenFold3, Boltz-1 and Protenix. Across 201,376 five-seed combinations from 32 seeds, 62.22% matched or exceeded 75% success, indicating robustness. Code and weights are on GitHub under Apache-2.0, with a hosted demo and finetuning scripts.
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