Ex-OpenAI researcher: biological-compute hype isn't a real ML breakthrough

willdepue · x · 2026-10-31

Jacob Hilton said he was surprised to see biological compute advertised as doing things it cannot yet do. Will Depue replied that training cheap video models and studying biological neurons have almost nothing to do with each other—like SwiGLU versus fly brain connectome research—and said he's confident these teams haven't made a foundational ML breakthrough.

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