Genomic in-context learning and CoT touted as a new frontier for generative biology

anshulkundaje · x · 2026-10-30

@garykbrixi highlights genomic in-context learning (ICL) and chain-of-thought as an exciting new approach for generative biology, sharing papers, code and a web app. Stanford professor Anshul Kundaje counters that while the ICL work is impressive, enhancer/promoter design can be done with simpler, faster cell-type-specific sequence-to-ontology models, questioning EVO2's necessity here.

Related event: Evo 2 exhibits emergent in-context learning, enabling few-shot genomic design(14 posts)→

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