Download before the 'cyber pandemic': a curated list of open science AI models

Promptmethus · x · 2026-10-28

Framed as a meme — 'download these before the internet gets restricted during the cyber pandemic' — this thread curates open-weight models worth keeping locally: genome models (Evo 2 40B/7B, Genos-1.2B/10B), pathology models (OpenMidnight, GenBio-PathFM), protein design (BoltzGen, text-to-protein Pinal), ESM-2 + ESMFold, plus orcarouter/Qwen3.8-27B-Uncensored-GGUF and the ARTEX autonomous penetration-testing system (GitHub, AGPL-3.0, 389 stars), with tips on choosing raw/paper/pdf versions based on storage.

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