Robert Plenge: How much causal human biology we know determines AI's role in drug discovery
rbhar90 · x · 2026-10-24
Geneticist Robert Plenge argues the answer to "what fraction of causal human biology do we actually know?" has no single number—only a structure. The key unexamined assumption in AI-for-drug-discovery debates: if we already know enough causal biology, AI just connects and interprets; if not, AI must discover genuinely new causal biology or be tightly coupled to physical experiments. Part 1 uses lipid and psychiatric genetics to frame the argument.
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