Chaperone design agent cuts token use 86%, yields 1.32 nM cortisol binder in two weeks

josephdviviano · x · 2026-10-21

A team unveiled Chaperone, a protein-design agent harness (Blocks, Examples, Skills) that handles small-molecule binding, nanoparticle scaffolding, and complex fusion tasks. It cut token usage by 86% on their benchmark and went from hypothesis to wet-lab-ready sequences in two weeks, producing a 1.32 nM cortisol binder in the first experimental round.

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