Transformer trained on flying bat recordings yields hippocampus 'digital twin' revealing hidden structure

patrickmineault · x · 2026-10-16

A new preprint builds a functional "digital twin" of the hippocampus by training a transformer on Neuropixels recordings and 3D flight trajectories from freely flying bats. Probing the model's latent space revealed previously unknown structure in hippocampal population activity: latent PC1-PC3 trajectories mirror the bats' physical XYZ position, and positive/negative motifs form separable loop-like structures. The work shows large-scale neural recordings can yield a probe-able model of hippocampal computation, offering a new tool for studying spatial coding and population dynamics.

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