Metabolic aging clock study: more physical activity linked to 2.5 years younger, fried food ages you
EricTopol · x · 2026-10-15
Eric Topol highlights a new Science Translational Medicine study on a metabolite-based aging clock, notable for longitudinal lifestyle data. The clock strongly predicts future health outcomes and tracks lifestyle: increased physical activity was associated with being 2.48 years metabolically younger, cutting fried food with 3.07 years younger, while new secondhand smoke exposure (+2.66y), worsening depressive symptoms (+0.56y/SD), and BMI shifting to overweight/obese (+1.77y) all accelerated metabolic aging.
Related event: Metabolite-Based Aging Clock Predicts Mortality and Chronic Disease Risk(2 posts)→
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