Even with ASI, 500 longevity hypotheses still need human testing on biology's clock

gregmushen · x · 2026-10-12

gregmushen runs a thought experiment: even if ASI generated 500 clever longevity hypotheses tomorrow, you'd still have to sort out which intervention gets humans to 200 without causing cancer, immune, metabolic or developmental pathology. Without a high-resolution map of biological systems (which we don't have), you eventually must test in humans — biology responds on biology time. He adds a paradox: ASI makes empirical science look slower, since hypothesis generation outruns reality-gated feedback loops.

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