Tenstorrent Blackhole folds 4x more per dollar than H200; antibody docking hits 84% top-1

DavidBennett__ · x · 2026-10-11

OpenDDE 1.2 is now live in TT-Bio and available to everyone on Japanfold. Per dollar, a Tenstorrent Blackhole Galaxy server folds about 4x more OpenDDE 1.2 structures than an Nvidia DGX H200.

The new guided docking feature takes a few known contacts and turns antibody docking from mostly failing into mostly right — top-1 success jumps from 19% to 84% on hard targets at almost no extra compute. Built by @itswillhua and AurekaBio.

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