GeneICL: lightweight tabular foundation model wins across 80 clinical transcriptomics tasks

anshulkundaje · x · 2026-10-07

A Stanford team (Anshul Kundaje's group) introduces GeneICL, a lightweight looped tabular foundation model for bulk transcriptomics, benchmarked on 80 classification, regression, and survival-prediction tasks. Key insight: self-supervised transcriptomic FMs pretrained on millions of profiles often lose to simple supervised baselines — the pretraining objective may matter more than scale.

Related event: GeneICL: Lightweight Transcriptomics Model Beats Larger Baselines(2 posts)→

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