Pre-LLM NLP predicts which psychedelic drug a trip report describes, far above chance

Josikinz · x · 2026-10-03

Researchers show that old-school pre-LLM NLP can identify the substance behind de-identified psychedelic trip reports an order of magnitude better than chance. Mispredictions are non-random too: subjectively similar drugs like MDA get mistaken for MDMA. After validating discrimination via report embeddings, they built a PLSR-based mapping of covariance between biochemistry and subjective experience, comparing drugs' positions in a multidimensional effect space.

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