Genomics MCP v0.1.0: 23 open-source tools let AI agents fetch genomic reads, variants and signal
Fair-Rain3366 · reddit · 2026-09-28
The author released Genomics MCP v0.1.0 (MIT-licensed), giving MCP clients direct access to genomic archives, installable via Python or Docker.
- 23 tools: dataset discovery across EGA, ENA, ENCODE, GEO, NCBI; bounded reads from BAM/CRAM, VCF/BCF, FASTA, bigWig/bigBed; reference evidence from ClinVar, Ensembl, gnomAD
- Demo: retrieved the exact mean signal for a 1 kb interval in a 1.4 GB ENCODE bigWig via HTTP range requests — no full file staged
- Results include provenance, limits, and partial errors, aiming to let research agents inspect real data reproducibly
- Built with Claude Code, then independently reviewed and validated against samtools/bcftools
Data-access layer only: no variant calling, no clinical decisions; controlled EGA data still requires approved access.
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