Octant essay: AI shifting drug discovery from lab-in-the-loop to agentic workflows

anshulkundaje · x · 2026-09-25

Octant founder Srinivas Kasetti's essay 'Mens et Manus' details how AI is reshaping the company: the team has evolved from lab-in-the-loop applications to more agentic ways of working on frontier drug programs, where you don't even know what question to answer. He opens with a thought experiment: could MIT's 1860s founders, given unmetered intelligence but only period knowledge, have said 'Claude, build a transistor'?

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