MEMOIR: open-source benchmark tests AI memory on 117 synthetic oncology patients

jefrankle · x · 2026-09-24

MEMOIR (Memory Evaluation over Multi-year Oncology Inference & Retrieval) is a new open-source benchmark for longitudinal clinical memory: 117 synthetic oncology patients, 65,377 clinical events, and 3,617 questions covering factual retrieval, rare-event detection, episode reconstruction, and longitudinal reasoning. The authors argue clinical memory differs structurally from conversational memory — histories span multiple systems, frequencies, and years. Evaluated approaches include vector memory (mem0), temporal knowledge graphs (Graphiti), and agent-managed memory (Letta).

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