DeepMind launches AlphaGenome 2 with major performance leap in variant-effect prediction
anshulkundaje · x · 2026-11-11
Google DeepMind's AlphaGenome 2 is live, described by researchers as a step change in performance and capabilities over AG1. The model predicts cell-type-specific regulatory activity and variant effects from DNA sequence, helping interpret non-coding variants against single-cell atlases.
- Manuscript, blog and API are available now
- Commercial API rolling out on Google Cloud in private preview
- Model weights and AG2 Skills in Antigravity will be released in the future; extra non-commercial API quota available by request
Related event: DeepMind launches AlphaGenome 2 for single-cell DNA variant prediction(12 posts)→
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