Nature Computational Science review maps four roles of LLMs as human proxies

iyadrahwan · x · 2026-09-22

A review by Karetnikov, Iyad Rahwan and Davor Svetinovic in Nature Computational Science organizes research that uses LLMs as human proxies into four roles: believable agents, task agents, experimental subjects, and silicon samples. It argues similarity to humans is not a single feature — each role supports different scientific claims and requires its own validity criteria.

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