Human organoids restore cognition in mice missing half their brain, Stanford finds

burny_tech · x · 2026-09-21

Sergiu Pașca's lab at Stanford engineered mice lacking over 90% of their cortex, then transplanted four human brain organoids grown from stem cells into about half of them. The grafts not only integrated into the host brains but restored most of the mice's cognition and movement.

Cambridge's Gabriel Balmuș, not involved in the work, noted the mice went from being 'relatively sick' without a cortex to behaving close to normal. The study was published in Nature.

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