Anthropic: Claude-optimized bio models run 4x faster with 100x less GPU time
BenBlaiszik · x · 2026-09-18
Anthropic's Science blog: Claude optimized 30+ open-source models for structure prediction and molecular design, making them 4x faster on average, with all optimization code open-sourced.
- Built FlashPairformer with Claude: 2.7-2.9x speedup on triangle attention and 1.7-3.2x on triangle multiplication, targeting the cubic-complexity ops dominating AlphaFold3/OpenFold3/Boltz-2 compute
- New low-memory "Big" mode folds molecular machines over 10,000 amino acids on a single GPU
- Claude achieves state-of-the-art molecule design with 100x fewer GPU hours
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