Human cortical organoids show large-scale integration in mouse brains, Nature reports

adeelrazi · x · 2026-09-17

A new Nature study introduces 'developmental xenocortication': human cortical organoids transplanted into mice with much of the endogenous cortex genetically depleted show extended large-scale integration, with brain-wide activity of human cells recorded in living mice. Neuroscientist Adeel Razi, commenting for The Australian, calls it an elegant platform for studying biological intelligence and disentangling which cortical properties are intrinsic to the human brain.

Related event: Stanford builds "xenocortical" mice with human organoids taking over ~92% of cortex(14 posts)→

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