Protein folding models ported to WebGPU: run AlphaFold predictions locally in your browser
sokrypton · x · 2026-09-17
The ColabFold author shipped a highly experimental WebGPU port (LocalFold) letting you run protein structure prediction models — AF3, Boltz-2, Protenix-v2, IntelliFold-2, RoseTTAFold3, OpenBind-0 and more — directly on your own laptop, with a drag-and-drop web UI and controls for MSA, recycles, sampler and seeds. Warning from the author: it will drain battery, overheat your machine, and eat your data plan. The effort started with Martin Steinegger's AF2 WebGPU port.
Related event: ColabFold 1.6.3 ships 2.5x speedup and WebGPU port(3 posts)→
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