Stanford's Anshul Kundaje: the open-model biosecurity dilemma has no good answer

anshulkundaje · x · 2026-09-17

Stanford professor Anshul Kundaje says his views on AI biosecurity shifted rapidly in recent months—not because of the millennium prize solution or the Hugging Face incident, but from in-person discussions with experts on both sides in neutral settings and reading serious long-form arguments.

His biggest disagreement is with crippling open models' bio knowledge: beyond the many reasons he thinks this is a bad idea, the harder unresolved problem is how to incentivize open-source efforts to implement safeguards as model capabilities improve.

Related event: Stanford Professor Kundaje Shifts to a Middle Ground on AI Biosecurity(5 posts)→

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