Foundation funds OpenADMET: open datasets and blind competitions to crack drug ADMET prediction
iskander · x · 2026-09-16
What's happening
Foundation (OpenAI's nonprofit arm) is funding OpenADMET, partnering with @srikosuri's team to build high-throughput methods measuring physicochemical properties and distribution, plus open datasets, benchmarks, and blinded competitions to test whether AI models can predict how small molecules are absorbed and move through the body.
Why it matters
- 90% of drug candidates fail in clinical trials, often due to hard-to-predict ADMET properties.
- Like AlphaFold2, unsolved prediction challenges paired with high-quality data are a good fit for AI.
- Goal: make drug development more predictable, cut failure rates, and drive the next wave of AI model improvements via blind competitions.
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