Five pharma companies fine-tune OpenFold3 federatively, lifting ligand-pose accuracy from 29% to 47%

AllThingsApx · x · 2026-09-14

Five pharma companies fine-tuned OpenFold3 in a federated setting on 20,000+ structures, raising correct ligand-pose predictions from 29% to 47%. The work builds on the OpenFold consortium, now backed by nearly 50 companies, and is reproducible thanks to open-source AI and Muhammad AlQuraishi's lab.

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