MIT team reports in Science how 3D folding of synthetic gene circuits shapes expression
anshulkundaje · x · 2026-09-13
- Galloway Lab at MIT published in Science on how the 3D folding of synthetic gene circuits influences gene expression.
- They introduce the idea of "gene syntax": how genes are arranged in sequence and space shapes feedback between transcriptional activity and genome folding.
- The aim is to add a structural design principle for building more advanced synthetic circuits.
More from Research
- Researcher: verifying 70–100-page proofs by hand takes months; AI could fix that — kfountou · 2026-09-13
- 16 Calls in One Hour: A Metacognitive Loop That Knows When to Stop Self-Correcting — Dzikula · 2026-09-13
- DeepSeek: working on data beats working on algorithms — burny_tech · 2026-09-13
- SemiAnalysis probes positional embeddings: what lies beyond common mathematical constraints? — burny_tech · 2026-09-13
- Upstream gene dominance: supercoiling-mediated repression gates downstream activation — anshulkundaje · 2026-09-13
- OpenAI open problem #2 cracked by human theorists; paper unifies and improves MRRW bounds — abeirami · 2026-09-13