MIT team reports in Science how 3D folding of synthetic gene circuits shapes expression
anshulkundaje · x · 2026-09-13
- Galloway Lab at MIT published in Science on how the 3D folding of synthetic gene circuits influences gene expression.
- They introduce the idea of "gene syntax": how genes are arranged in sequence and space shapes feedback between transcriptional activity and genome folding.
- The aim is to add a structural design principle for building more advanced synthetic circuits.
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