Running Qwen 27B and Gemma 31B locally on one RTX 4090: quantization and context tradeoffs

MooseEfficient2151 · reddit · 2026-09-08

A Reddit user with an RTX 4090 (24GB), 64GB DDR5 and a Ryzen 7950x wants to shift code indexing and internal doc processing from external APIs to local models for privacy. Qwen 3.6 27B runs smoothly at Q4 in VRAM, but larger dense models and gpt-oss 20b with context offloading tank generation speed. They ask for vLLM/llama.cpp backend and quantization setups that balance context size and tok/s on a single card.

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