Full 166,700-neuron fruit fly connectome runs inside Minecraft

birchlse · x · 2026-09-08

Developer evnsnclr reports running the full retained MaleCNS v1.0 fruit fly connectome — all 166,700 neurons — inside Minecraft, with its simulated neural activity driving a fly's movement. V1 is in development, built with the help of GPT-6 Astra, with code and a mod coming soon; he credits the OpenAI team and thsottiaux.

Quoter jackwhitcomb adds a key caveat: this isn't a true simulation of a fruit fly brain — since we lack the brain's real weights, it's fruit fly-esque software built on the connectome's structure.

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